Tag: fibroid

1. While women in both groups experienced dramatic gains in fibroid-related quality of life, the magnitude of the increase was greater in the myomectomy group versus the embolization group. 2. Surgical reintervention was necessary in a greater percentage of the embolization group. Evidence Rating Level: 1 (Excellent) Study Rundown: Uterine fibroids are...
1. In this pair of identical phase 3 trials involving premenopausal women with uterine fibroids, both elagolix with and without add-back therapy was more effective in reducing heavy menstrual bleeding than placebo. 2. Significant decreases in bone mineral density were observed in the group that received elagolix without add-back therapy,...
1. In this pair of identical phase 3 trials involving premenopausal women with uterine fibroids, both elagolix with and without add-back therapy was more effective in reducing heavy menstrual bleeding than placebo. 2. Significant decreases in bone mineral density were observed in the group that received elagolix without add-back therapy,...
1. Leiomyoma cells treated with simvastatin exhibited increased apoptotic activity and decreased proliferative activity. 2. Mice treated with simvastatin had decreased leiomyoma growth and decreased proliferative tumor activity. Evidence Rating Level: 2 (Good)   Study Rundown: Uterine fibroids, or leoiomyomas, are benign tumors found in women of reproductive age. While some women...
1. Morcellation within a contained, insufflated bag was successfully reproduced in 73 minimally invasive gynecologic surgeries at multiple institutions.  2. In all surgeries, the technique was not associated with complications or visual evidence of tissue dissemination.  Evidence Rating Level: 4 (Below Average)          Study Rundown: Minimally invasive routes of surgery, such as laparoscopic...