Antibiotic therapy is inferior to surgery for children with uncomplicated appendicitis
1. Treatment failure was greater in the antibiotic group compared to appendicectomy group. 2. Significantly more patients in the antibiotic ...
Tag: general surgery
24-hour delay may be safe for surgical intervention in patients with uncomplicated appendicitis
1. Operating within 24 hours was non-inferior to operating within 8 hours among patients diagnosed with uncomplicated appendicitis with respect ...
2-day antibiotic non-inferior to 5-day antibiotic therapy for postoperative management of complex appendectomy
1. The rate of infectious complications and mortality at 90 days was similar between groups. 2. No treatment-related deaths were ...
Bepirovirsen may reduce disease burden in patients with chronic hepatitis B
1. Bepirovirsen resulted in a sustained hepatitis B surface antigen (HBsAg) and hepatitis B virus (HBV) DNA loss in approximately ...
Removal of asymptomatic kidney stones reduces risk of relapse
1. In a group of patients undergoing endoscopic removal of symptomatic kidney stones, concurrent removal of asymptomatic stones significantly reduced ...
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Germline mutations in CIDEB confer protection from liver disease
1. Rare mutations in CIDEB are associated with a decreased risk of developing liver cirrhosis. 2. Further, rare mutations in ...
Laparoscopic sigmoid resection for recurrent diverticulitis associated with higher quality of life scores
1. Patients with recurrent diverticulitis have higher quality of life scores after undergoing elective laparoscopic sigmoid resection, compared to a ...
Quick Take: Restrictive strategy versus usual care for cholecystectomy in patients with gallstones and abdominal pain (SECURE)
Laparoscopic cholecystectomy for the treatment of symptomatic cholecystolithiasis is currently the standard of care. However, multiple studies indicate that 10-41% ...