Tag: gestational diabetes

1. A modestly lower carbohydrate diet neither increased ketonemia nor improved glycemic control in pregnant women Evidence Rating Level: 2 (Good) Although meta-analyses have shown significant improvements in HbA1c and greater weight loss with low-carbohydrate diets in the context of type 2 diabetes and obesity, there is a lack of consensus...
The association between use of proton-pump inhibitors and excess mortality after kidney transplantation: A cohort study 1. PPI use may be associated with an increased mortality risk in patients who have received kidney transplants. Evidence Rating Level: 1 (Excellent) Proton-pump inhibitors (PPIs) are commonly prescribed to kidney transplant recipients (KTRs) to protect...
1. Study findings suggest gestational diabetes is associated with larger fetal size starting at week 20, and that efforts to mitigate associated fetal growth should start between 24-28 gestational weeks. Evidence Rating: 1 (Excellent) Maternal glucose concentrations have been found to be positively associated with birth weight, with mothers with gestational diabetes...
Severe Lung Injury Associated With Use of e-Cigarette, or Vaping, Products - California, 2019 1. Study findings suggest that use of THC-containing products and vitamin E acetate to be associated with outbreak of use-associated lung injury in California Evidence Level: 3 (Average): Despite e-cigarette, or vaping usage increasing in popularity in North...
While obesity has been shown to increase the risk of developing gestational diabetes mellitus (GDM) and preeclampsia (PE) in pregnancy, the association between metabolic syndrome and adverse pregnancy outcomes has not been investigated. In this multicenter prospective cohort study, 5,530 nulliparous women with singleton pregnancies recruited between November 2004...
1. Maternal prepregnancy obesity without pregestational diabetes mellitus (PGDM) or gestational diabetes mellitus (GDM) was associated with a slightly increased risk of having a child with a neurodevelopmental or psychiatric disorder. 2. Mothers with severe obesity and insulin-dependent, pregestational diabetes had a sixfold increased risk of having a child with...
1. In this randomized controlled trial, glyburide was not non-inferior in terms of the composite rate of macrosomia, neonatal hypoglycemia, and hyperbilirubinemia compared with subcutaneous insulin. 2. Women taking glyburide had better glycemic control and were more likely to prefer glyburide for subsequent pregnancies but also had higher rates of...
1. In this prospective cohort study, history of gestational diabetes (GDM) was associated with increased risk of cardiovascular disease (CVD) later in life. 2. After adjustment, women with GDM who did not go on to developing Type 2 Diabetes (T2DM) did not have an increased CVD risk, whereas women with...
1. Women receiving dietary counseling and exercise classes had less gestational weight gain than those receiving standard prenatal care. 2. There were no differences in gestational diabetes, operative delivery or birth weight between intervention arms. Evidence Rating Level: 1 (Excellent) Study Rundown: Excessive gestational weight gain has been associated with adverse maternal...
Classics Series, Landmark Trials in Medicine
1. Among women with gestational diabetes requiring treatment, those randomized to glyburide achieved similar glycemic control to women in the insulin control group. Original Date of Publication: October 2000 Study Rundown: The adverse pregnancy outcomes associated with diabetes have been well documented. Following diagnosis, women with gestational diabetes mellitus are initially...