Tag: Major Depression

1. In this systematic review and meta-analysis, pooled analysis of placebos for treatment-resistant depression demonstrated a large effect size, but no significant difference between placebo modalities. Evidence Rating Level: 1 (Excellent) Study Rundown: Randomized controlled trials (RCTs) compare a drug’s efficacy to a placebo to isolate the effect of the drug...
1. The findings of this longitudinal cohort study suggest an association between atopic dermatitis and symptoms of depression and internalizing behaviors starting in early childhood and persisting through adolescence. 2. With the global prevalence of atopic diseases increasing in children, health care providers must be cognizant of the psychosocial needs...
1. This meta-analysis found increased prevalence rates of clinically elevated anxiety and depression symptoms among youth during the COVID-19 pandemic. 2. Higher prevalence rates in data collected later in the pandemic, older adolescents, and females, as determined through moderator analysis, suggested that individual differences need to be considered when determining...
1. This meta-analysis found increased prevalence rates of clinically elevated anxiety and depression symptoms among youth during the COVID-19 pandemic. 2. Higher prevalence rates in data collected later in the pandemic, older adolescents, and females, as determined through moderator analysis, suggested that individual differences need to be considered when determining...
1. In this randomized controlled trial, overweight or obese adults with subsyndromal depressive symptoms were just as likely to develop major depressive disorder (MDD) when treated with food-related behavioral activation therapy plus dietary supplementation than care as usual. 2. Food-related behavioral activation therapy was related to a significant improvement in...
Originally published by Harvard Health.   What Is It? The most prominent symptom of major depression is a severe and persistent low mood, profound sadness, or a sense of despair. The mood change can sometimes appear as irritability. Or the person suffering major depression may not be able to take pleasure in activities...