Tag: obesity

Preterm birth is the leading cause of infant mortality and neonatal morbidity. Maternal obesity is associated with an increased risk of gestational diabetes and hypertensive disorders of pregnancy, which can, in turn, contribute to medically indicated preterm birth. As such, pre-pregnancy obesity represents a potentially modifiable risk factor for...
Patients with schizophrenia that do not respond to 2 or more antipsychotics are considered to have treatment-resistant disease. In these settings, clozapine, an atypical antipsychotic, is typically used. However, a number of randomized clinical trials comparing clozapine with other non-clozapine second generation antipsychotics (NC-SGAs), have recently put into question...
1. Increases in body mass index (BMI) were associated with all-cause mortality among the Hispanic population included in this prospective study. 2. Abdominal adiposity was found to be a particularly strong major risk factor for premature death within this population, even after adjustment for BMI and hip circumference. Evidence Rating Level:...
Efficacy of prehospital criteria in identifying trauma patients susceptible to undertriage While the early recognition of severe traumatic injury is associated with improved morbidity and mortality, undertriage has been associated with poorer patient outcomes. Previous research has shown that tachypnea and blunt thoracic injury are associated with undertriage. In this...
While numerous studies have previously examined associations between physical activity and mortality, cardiovascular disease and certain cancers, the majority of this evidence has been cross-sectional, single-timepoint data, or has relied on a single baseline physical activity assessment for correlation. Few studies have examined physical activity trajectories over time, and...
Protective intraoperative mechanical ventilation has been associated with reduced postoperative pulmonary complication risk. Obesity is associated with an increased risk of atelectasis and impaired respiratory function. In this setting, high positive end-expiratory pressure with alveolar recruitment maneuvers have been proposed for routine intraoperative mechanical ventilation to prevent these physiologic...
Ultra-processed food intake and risk of cardiovascular disease: prospective cohort study (NutriNet-Santé) The consumption of ultra-processed food has increased substantially over the last several decades. These foods often have higher proportions of total and saturated fat, added sugar, energy density and salt, and lower proportions of fibre and vitamin density....
Roux-en-Y gastric bypass (RYGB) is associated with significant bone loss and may increase fracture risk as a result. This is in contrast to other bariatric procedures, such as adjustable gastric banding (AGB), which has not been found to confer the same fracture risk to date. In this retrospective cohort...
1. In this serial, cross-sectional analysis, US youths had improved triglycerides, LDL, HDL, and total cholesterol from 1999 to 2016. 2. While half of all US youths had ideal lipid levels, nearly a quarter had at least one unfavorable lipid measure. Evidence Rating Level: 2 (Good) Study Rundown: Optimal lipid levels help...
1. In this randomized controlled trial, integrated behavioral weight loss treatment, problem-solving therapy, and as needed antidepressant treatment led to a modest reduction in depression symptoms and weight loss at 12 months compared to care as usual. 2. The intervention was successful in non-Hispanic white patients, women, and those older...