Tag: pneumonia

1. Among children with community-acquired pneumonia, proadrenomedullin more accurately predicted severe disease than established biomarkers such as C-reactive protein and procalcitonin. Evidence Rating Level: 2 (Good) Study Rundown: Health care encounters for community-acquired pneumonia (CAP) among children are both frequent and costly. Though clinical biomarkers like white blood cell count (WBC),...
1. Three-day amoxicillin treatment for chest-indrawing pneumonia was not significantly different from five-day amoxicillin treatment in HIV-uninfected children from Malawi. 2. Relapse for pneumonia was not significantly different between treatment groups. Evidence Rating Level: 1 (Excellent) Study Rundown: Bacterial pneumonia is one of the leading causes of death for children under the...
1. Nearly all patients hospitalized for community-acquired pneumonia have at least one risk factor for aspiration, though few present with clinical aspiration pneumonia. 2. Bacterial isolates from patients hospitalized with aspiration community-acquired pneumonia do not support the use of anti-anaerobic coverage, despite widespread use among such patients. Evidence Rating Level: 2...
1. In a study of children with pneumonia or sinusitis, opioids and corticosteroids were inappropriately prescribed more frequently in the emergency department (ED) for both conditions compared to the ambulatory setting. 2. Overall, 1 in 16 children with pneumonia and 1 in 13 children with sinusitis were prescribed an opioid...
1. In this noninferiority study, children who received placebo for pneumonia with tachypnea had a higher incidence of treatment failure compared to those who received amoxicillin. 2. Numerically, more relapses occurred in the amoxicillin control group, but the between-group difference was not statistically significant. Evidence Rating Level: 1 (Excellent) Study Rundown: The...
1. In a study of children with pneumonia or sinusitis, opioids and corticosteroids were inappropriately prescribed more frequently in the emergency department (ED) for both conditions compared to the ambulatory setting. 2. Overall, 1 in 16 children with pneumonia and 1 in 13 children with sinusitis were prescribed an opioid...
1. Three-day amoxicillin treatment for chest-indrawing pneumonia was not significantly different from five-day amoxicillin treatment in HIV-uninfected children from Malawi. 2. Relapse for pneumonia was not significantly different between treatment groups. Evidence Rating Level: 1 (Excellent) Study Rundown: Bacterial pneumonia is one of the leading causes of death for children under the...
1. In a study of children with community acquired pneumonia, initial biomarker levels (C-reactive protein, white blood cell count, procalcitonin, absolute neutrophil count) were similar across illness severities. 2. Higher C-reactive protein and procalcitonin levels were predictive of specific severe outcomes, including empyema requiring chest drainage and septic shock. Evidence Rating...
1. Children with COVID-19 tended to have milder clinical manifestations, with nearly half of the infected cohort being asymptomatic. 2. Children with COVID-19 had a significantly lower prevalence of cough, fever, pneumonia, and CRP elevation compared to adults. Evidence Rating: 3 (Average) The clinical and characteristics of children affected by COVID-19 are...