Tag: Transcatheter aortic valve replacement

1. Among patients at intermediate surgical risk, transcatheter aortic valve replacement (TAVR) was shown to be noninferior to surgery with respect to the primary end point of death or disabling stroke at 24 months. 2. Patients who underwent surgery had higher rates of acute kidney injury, atrial fibrillation, and transfusion,...

1. Among all patients undergoing transcatheter aortic valve replacement, an increased risk of infective endocarditis was found in males, younger age groups, those with a history of diabetes mellitus, and those with aortic regurgitation. 2. Those patients who developed infective endocarditis had a significantly elevated rate of in-hospital mortality and...

1. The number and volume of new brain lesions was lower in patients with an implanted cerebral protection device following transcatheter aortic valve implantation 2. There was no difference in the rate of complications in patients with the cerebral protection device compared to controls.   Evidence Rating Level: 1 (Excellent) Study Rundown:...

1. Closure time with adenosine diphosphate (CT-ADP) measurement after a transcatheter aortic-valve replacement (TAVR) procedure was predictive of patients with paravalvular aortic regurgitation. 2. Elevated CT-ADP times were more predictive of patient death 1 year post-TAVR than aortic or mitral regurgitation. Evidence Rating: 1 (Excellent) Study Rundown: Following a TAVR for treatment...

1. For intermediate-risk surgical candidates with aortic stenosis, transcatheter aortic-valve replacement (TAVR) was non-inferior to surgical aortic-valve replacement based on all-cause death and disabling stroke at 2 years, as well as 30-day clinical endpoints. 2. TAVR had better aortic valve area and gradient compared to surgery based on echocardiographic...

1. In this secondary analysis of the PARTNER trial, women who underwent transcatheter aortic valve replacement (TAVR) had more major vascular complications, major bleeding events that caused death or disability and increased unplanned arterial procedures, but fewer paravalvular leaks, than men. 2. At 1 year, women had lower all-cause mortality and...

1. One year after transcatheter aortic valve replacement (TAVR), the incidence of stroke was 4.1%, overall mortality was 23.7% and 46.8% of patients who were alive had not been rehospitalized. 2. Several baseline characteristics were independently associated with 1-year mortality, including advancing age, severe lung disease, end-stage renal disease,...

1. When compared with bioprosthetic aortic valve replacements (AVR), mechanical AVRs were associated with increased mortality on the date of surgery and in early days after the operation amongst older Americans. 2. This difference in mortality was not present between the two forms of AVR 30 days after the...

Image: PD In this section, we will highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Multistate Point-Prevalence Survey of Health Care-Associated Infections Health care-associated infections are widespread, but no universal surveillance system is in place to monitor the status of such infections on a national...

Image: PD/CDC/Aortic Stenosis 1. According to this systemic review, transcatheter aortic valve replacement (TAVR) is associated with a decrease in New York Heart Association (NYHA) functional class, but only a minor improvement in quality of life (QOL).    Evidence Rating Level: 1 (Excellent)  Study Rundown: Surgical aortic valve replacement (SAVR) is the...