• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home StudyGraphics

#VisualAbstract: Mobile stroke units associated with better outcomes for acute ischemic stroke management

byMinjee Kim
February 17, 2022
in StudyGraphics
Reading Time: 3 mins read
0
Share on FacebookShare on Twitter

1. Compared with usual care, mobile stroke unit deployment was associated with a significant increase in the odds of excellent outcome, a higher proportion of treatment via intravenous thrombolysis, and a 30-minute reduction in onset-to-thrombolysis times, without safety concerns

2. However, it must be recognized that mobile stroke unit implementation is associated with significant costs and requires specialized training and optimal integration into regional emergency response services.

Evidence Rating Level: 1 (Excellent)

Study Rundown: The mobile stroke unit (MSU), largely based on the ‘time-is-brain’ concept in acute stroke, was first implemented in the early 2000s. It involves a specialized ambulance equipped with computed tomography technology, point-of-care laboratory, and neurological expertise to expedite workup and recanalization in acute ischemic stroke. It is now available in several regions across the world; however, uncertainty remains as to whether there is sufficient evidence to suggest better functional outcomes with MSU deployment compared with usual care – especially given the high costs of acquiring and maintaining them. This systematic review and meta-analysis assessed the magnitude of benefit from shifting acute stroke management into the prehospital phase of care with MSUs in comparison with usual care. The main endpoint was excellent outcome measured using the modified Rankin Scale (mRS; score of 0 to 1 at 90 days). Overall, MSU deployment was significantly associated with an approximately 65% increase in the odds of excellent outcome at 90 days, a higher proportion of intravenous thrombolysis (IVT), and a reduction of 31 minutes in onset-to-IVT time, without safety concerns. These findings may help inform clinicians and decision makers in creating safe and evidence-based guidelines on prehospital stroke care. A limitation of this study was that literature and data on MSU deployment vs standard care was limited, as the concept is still relatively recent and has not been widely implemented across the world. Furthermore, available data did not always report on consistent functional outcomes and objective measures for pooled analysis.

Click to read the study in JAMA Neurology

Relevant Reading: Diagnosis and treatment of patients with stroke in a mobile stroke unit versus in hospital: a randomised controlled trial

RELATED REPORTS

Improved mortality rates for myocardial infarction, stroke, and pulmonary embolism in patients receiving dialysis between 1998 to 2015

Reduced bleeding risk with asundexian compared to apixaban in patients with atrial fibrillation

Large vessel occlusion stroke is associated with poor prognosis in children

In-Depth [systematic review and meta-analysis]: This review included 14 articles comparing MSU use vs usual care for suspected stroke management from a search of MEDLINE, Cochrane Library, and Embase between 1960 to 2021. Data extraction was performed by 2 independent reviewers following the PRISMA and MOOSE reporting guidelines and the risk of bias was determined using the ROBINS-I and RoB2 tools. Data were then pooled in random-effects meta-analyses. Compared with usual care, MSU deployment was associated with excellent outcome (aOR, 1.64; 95%CI, 1.27-2.13; P < .001; 5 studies; n = 3228), reduced disability over the full range of the mRS (aOR, 1.39; 95%CI, 1.14-1.70; P = .001; 3 studies; n = 1563), good outcome (mRS score of 0 to 2: crude OR, 1.25; 95%CI, 1.09-1.44; P = .001; 6 studies; n = 3266), shorter IVT times (median reduction, 31 minutes [95%CI, 23-39]; P < .001; 13 studies; n = 3322), delivery of IVT (crude OR, 1.83; 95%CI, 1.58-2.12; P < .001; 7 studies; n = 4790), and IVT within 60 minutes of symptom onset (crude OR, 7.71; 95%CI, 4.17-14.25; P < .001; 8 studies; n = 3351). Additionally, MSU deployment was not associated with an increased risk of all-cause mortality at 7 or 90 days or symptomatic intracranial hemorrhage after IVT.

©2022 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: Golden hourIVTmobile stroke unitmRSMSURankin Scalestrokethrombolysis
Previous Post

Hyperimmune immunoglobulin does not improve outcomes in patients hospitalized with COVID-19

Next Post

Wellness Check: Nutrition

RelatedReports

Fish oil and aspirin did not reduce arteriovenous fistula failure: The FAVOURED trail
Cardiology

Improved mortality rates for myocardial infarction, stroke, and pulmonary embolism in patients receiving dialysis between 1998 to 2015

April 22, 2022
Stroke expansion following intra-arterial therapy may explain worse outcomes
Cardiology

Reduced bleeding risk with asundexian compared to apixaban in patients with atrial fibrillation

April 19, 2022
Combined MRI and NIH stroke scores may predict stroke prognosis
Emergency

Large vessel occlusion stroke is associated with poor prognosis in children

March 29, 2022
Intensive rehabilitation not superior to traditional therapy for arm function after stroke
Cardiology

Increased risk of intracranial hemorrhage with aspirin and unfractionated heparin use for endovascular stroke treatment

March 22, 2022
Next Post
Provision of medically-tailored meals linked with lower admissions and medical spending

Wellness Check: Nutrition

#VisualAbstract: Individualized dosing of anti-thymocyte globulin may improves outcomes of allogeneic haematopoietic stem-cell transplantation in children

#VisualAbstract: Individualized dosing of anti-thymocyte globulin may improves outcomes of allogeneic haematopoietic stem-cell transplantation in children

Diffusion tensor imaging valuable in the evaluation of peripheral neuropathy

Traumatic brain injury associated with increased all-cause mortality risk for military veterans

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

Get 2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Pelvic lymph node radiotherapy and androgen deprivation therapy augment progression-free status following prostatectomy
  • Operating the day after performing surgery the previous night not associated with adverse patient outcomes
  • Gratitude-focused writing may improve mental wellness during periods of chronic stress
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.