• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home StudyGraphics

#VisualAbstract: Preterm formula is similarly effective to human milk fortifiers as breastmilk supplement

bySuchita Nety
June 24, 2021
in StudyGraphics
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Low-weight infants fed with breast milk supplemented with pre-term formula had noninferior weight gain compared to infants fed with breast milk supplemented with commercial human milk fortifiers (HMF).

2. The incidence of feed intolerance was lower in low-weight infants fed with breast milk supplemented with pre-term formula compared to infants fed with breast milk supplemented with HMF.

Evidence Rating Level: 1 (Excellent)

For low-birth weight infants, human milk does not provide adequate nutrients at usual feeding volumes. Therefore, several human milk fortifiers (HMF) have been developed as breast milk supplements to supply high nutrient requirements of low-birth weight infants. However, HMFs do pose potential risk of complications such as feed intolerance and necrotizing enterocolitis (NEC) and are very costly, which may preclude accessibility in low-and-middle income countries.

This new noninferiority randomized trial was conducted to determine if preterm formula (PTF) was as clinically effective as HMF supplementation. 123 low-birth weight infants receiving at least 100 ml/kg/d of feeds and consuming 75% of milk or more were randomized to breast milk fortified with PTF (60 participants) or HMF (63 participants). Neonates with major congenital abnormalities were excluded. The primary outcome was rate of in-hospital weight gain from randomization. Overall, there was no difference in weight gain observed between groups up to time of discharge or at 40 weeks’ corrected gestational age. Furthermore, infants in the PFT group had lower incidence of complications such as feed intolerance and NECs. Lastly, the cost differential for PTF was around $0.3 per day, which was significantly lower than that of HMF (around $4 per day). Overall, these findings demonstrated that PFT was a non-inferior, safe, and lower-cost fortification strategy that may be more widely accessible and used. However, a study with longer post-discharge follow-up and a systematic cost-effectiveness analysis would be needed to better understand the clinical efficacy and feasibility of implementing this measure globally. 

Click to read the study in JAMA Pediatrics

RELATED REPORTS

#VisualAbstract: Mydriatic Microdrops are Non-inferior for Retinopathy of Prematurity Screening Compared to Standard Drops

Prenatal Systemic Glucocorticoid Exposure and an Increased Risk of Future Mental Disorders

Small long term increased risks of neurodevelopmental deficits for infants born preterm

Image: PD

©2021 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: breast milkformulahuman milk fortifier (HMF)milkpreterm
Previous Post

#VisualAbstract: Upadacitinib plus topical corticosteroids is safe and effective for moderate-to-severe atopic dermatitis;

Next Post

A prospective evaluation of clinical HEART score agreement, accuracy, and adherence in emergency department chest pain patients

RelatedReports

#VisualAbstract: Mydriatic Microdrops are Non-inferior for Retinopathy of Prematurity Screening Compared to Standard Drops
StudyGraphics

#VisualAbstract: Mydriatic Microdrops are Non-inferior for Retinopathy of Prematurity Screening Compared to Standard Drops

January 20, 2025
Prenatal Systemic Glucocorticoid Exposure and an Increased Risk of Future Mental Disorders
StudyGraphics

Prenatal Systemic Glucocorticoid Exposure and an Increased Risk of Future Mental Disorders

January 16, 2025
Paternal factors associated with short interpregnancy interval
Chronic Disease

Small long term increased risks of neurodevelopmental deficits for infants born preterm

February 1, 2024
Eating in the absence of hunger linked to toddler obesity
Pediatrics

Dietary factors early in life may influence the development of celiac disease

December 11, 2023
Next Post

A prospective evaluation of clinical HEART score agreement, accuracy, and adherence in emergency department chest pain patients

Digital imaging detects sight-threatening retinopathy of prematurity

Fetoscopic endoluminal tracheal occlusion improves infant survival for congenital diaphragmatic hernia

Home visits in Ghana improve neonatal mortality

Immediate kangaroo mother care decreased mortality in low-birth-weight infants

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Seventh cervical nerve neurotomy may augment speech therapy in patients with chronic aphasia post-stroke
  • Time-restricted eating does not confer changes in sleep, mood, or quality of life
  • Commonly cited medication triggers may not increase risk of microscopic colitis among older adults
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.