Pediatrics Classics

Physician-written reports of landmark pediatrics studies

Antenatal steroids for fetal lung maturity [Classics Series]

1. Respiratory distress syndrome (RDS) and perinatal mortality were significantly less common among preterm infants whose mothers received betamethasone prior to delivery.Original Date...
Classics Series, Landmark Trials in Medicine

Adverse childhood exposures associated with poor health in adulthood [Pediatrics Classics Series]

1. Among 8056 adult patients who completed a standardized questionnaire regarding adverse childhood exposures, a significant dose-response relationship was observed when the number of...
Classics Series, Landmark Trials in Medicine

Antibiotic GBS prophylaxis linked to decreased early-onset neonatal infection [Pediatrics Classics Series]

Image: PD1. During the 1990-1998 study period, which included the 1996 initiation of national Group B Streptococcus guidelines, a significant, 65% decrease in early-onset...
Classics Series, Landmark Trials in Medicine

Standardized cost-effective model for diagnosing and treating febrile infants [Pediatrics Classics Series]

Image: PD1. Following implementation of an evidence-based care process model for evaluation and treatment of febrile infants, children were found to have significantly shorter...
Classics Series, Landmark Trials in Medicine

CT scans associated with increased risk of malignancy [Pediatrics Classics Series]

Image: PD1. Through a retrospective cohort analysis of children and young adults without previous malignancy, patients exposed to multiple CT scans were found to...

Initial trial of conservative management of splenic injury [Pediatrics Classics Series]

Image: PD1. The conservative, symptomatic management of 16 patients following assumed splenic injury from blunt abdominal trauma resulted in normalization of hemodynamic stability within...

Laboratory values and treatment associated with DKA-related cerebral edema [Pediatrics Classics Series]

Image: PD1. Among children admitted to 1 of 10 medical centers for diabetic ketoacidosis management, elevated serum urea nitrogen concentrations and low partial pressures...

Early infant CF diagnosis associated with improved nutritional status [Pediatrics Classics Series]

Image: PD1. Among infants randomized to undergo either newborn screen with cystic fibrosis (CF) testing included or undergo normal pediatric surveillance, those who underwent...

Prone sleeping position and heavy bedding associated with SIDS [Pediatrics Classics Series]

Image: PD1. In a study of sudden death in infants compared to matched controls, a significant increase in risk of death from unknown causes...
Classics Series, Landmark Trials in Medicine

Childhood febrile seizure characteristics associated with epilepsy diagnosis [Pediatrics Classics Series]

Image: PD1. Through the inclusion of infants from the Collaborative Perinatal Project, this large, multicenter, prospective study found that children with febrile seizures, complex...
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