Exenatide does not slow Parkinson’s disease progression compared to placebo
1. There was no significant difference in functional outcome between both groups at 96 weeks. 2. Exenatide was safe and...
Pediatrics Classics
Physician-written reports of landmark pediatrics studies
Triptans may be the most effective treatments available for acute episodic migraine
1. In this systematic review and meta-analysis, the combination of triptans and non-steroidal anti-inflammatory drugs (NSAIDs) was the most effective...
Adjunctive middle meningeal artery embolization superior to standard care in symptomatic chronic subdural hematomas
1. In this randomized controlled trial, middle meningeal artery embolization demonstrated a decreased risk of treatment failure in patients with...
Cabozantinib significantly improves progression free survival in patients with advanced neuroendocrine tumors
1. In this randomized controlled trial, cabozantinib significantly improved progression-free survival in patients with progressive pancreatic and extra-pancreatic neuroendocrine tumors....
Balloon-guided catheters are associated with worse outcomes in large vessel thrombectomy
1. Functional recovery at 90 days was lower in the balloon-guided catheter group versus the conventional catheter group. 2. All-cause...
Patient values and preferences when considering migraine prevention options
1. In this systematic review, patients with episodic migraine preferred oral pharmacologic treatments that reduced the severity, frequency, and duration...
No significant differences between medications for episodic migraine prophylaxis
1. In this systematic review and meta-analysis, there were no significant differences between various pharmacologic treatments for preventing episodic migraine...
Middle meningeal artery embolization reduces adverse events in patients with subdural hematomas
1. In this randomized controlled trial, among patients with symptomatic nonacute subdural hematoma, embolization of the middle meningeal artery (MMA)...
Adjunctive middle meningeal artery embolization may reduce the recurrence of subdural hematomas
1. In this randomized controlled trial, middle meningeal artery embolization plus surgical evacuation was associated with a lower risk of hematoma...
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PECARN Prediction rules for children at a low risk of clinically-important traumatic brain injury [Classics Series]
This study summary is an excerpt from the book 2 Minute Medicine's The Classics in Medicine: Summaries of the Landmark...