Surgery Classics

Physician-written reports of landmark surgery studies

The Child-Pugh score: Prognosis in chronic liver disease and cirrhosis [Classics Series]

1. The Child-Pugh score consists of five clinical features and is used to assess the prognosis of chronic liver disease and cirrhosis. 2. The Child-Pugh...
Classics Series, Landmark Trials in Medicine

The POISE trial: Perioperative use of beta-blockers [Classics Series]

1. The POISE trial was a randomized controlled trial exploring the effect of perioperative beta-blockers on cardiac death, nonfatal myocardial infarctions, and nonfatal cardiac...

The NASCET: Carotid endarterectomy for symptomatic stenosis [Classics Series]

Image: PD 1. Carotid endarterectomy, in addition to medical therapy, significantly reduces risk of major and fatal stroke in patients with symptomatic, high-grade (70-99%) carotid...

The CREST trial: Stenting versus endarterectomy for carotid stenosis [Classics Series]

Image: PD 1. The rate of stroke, myocardial infarction or death did not differ significantly between patients treated with carotid artery stenting compared to carotid...
Classics Series, Landmark Trials in Medicine

The ARMA trial: Lower tidal volume ventilation in ALI/ARDS [Classics Series]

1. The trial was terminated early when the data demonstrated that lower tidal volume ventilator settings in ALI/ARDS patients led to a significant decrease...
Classics Series, Landmark Trials in Medicine

The Lee index: Risk of perioperative cardiac events [Classics Series]

1. The Lee index is a prospectively validated model that predicts the risk of a cardiac event in patients undergoing noncardiac surgery. 2. The six...
Classics Series, Landmark Trials in Medicine

Vena caval filters in pulmonary embolism prophylaxis [Classics Series]

Image: PD 1. Permanent vena caval filter placement in addition to anticoagulant therapy helps prevent short-term occurrence of pulmonary embolism but increases the risk of...

The SYNTAX trial: CABG superior to PCI in triple-vessel or left main artery disease...

Image: CC/L.academia 1. In severe coronary artery disease, CABG is superior to PCI in reducing the need for repeat vascularization 2. CABG should remain the standard...
Classics Series, Landmark Trials in Medicine

The MELD score: Predicting survival in end-stage liver disease [Classics Series]

Image: PD 1. The Model for End-Stage Liver Disease (MELD) is a reliable tool for predicting short-term survival in patients with advanced liver disease 2. The...

The EVAR I trial: Endovascular vs. open abdominal aortic aneurysm repair [Classics Series]

Image: PD 1. The EVAR I trial compared the safety and efficacy of endovascular and open abdominal aortic aneurysm repair 2. There were no significant differences...
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