Surgery Classics

Physician-written reports of landmark surgery studies

Classics Series, Landmark Trials in Medicine

The POISE trial: Perioperative use of beta-blockers [Classics Series]

1. The POISE trial was a randomized controlled trial exploring the effect of perioperative beta-blockers on cardiac death, nonfatal myocardial infarctions, and nonfatal cardiac...
Classics Series, Landmark Trials in Medicine

The Lee index: Risk of perioperative cardiac events [Classics Series]

1. The Lee index is a prospectively validated model that predicts the risk of a cardiac event in patients undergoing noncardiac surgery. 2. The six...

No survival difference in lumpectomy and mastectomy for breast cancer [Classics Series]

Image: PD 1. In women with stage I or II breast cancer, there was no significant difference in overall survival in women treated with total...

The SYNTAX trial: CABG superior to PCI in triple-vessel or left main artery disease...

Image: CC/L.academia 1. In severe coronary artery disease, CABG is superior to PCI in reducing the need for repeat vascularization 2. CABG should remain the standard...

Intravenous omeprazole after endoscopy reduces rebleeding in patients with peptic ulcers [Classics Series]

Image: CC/L. academia 1. After endoscopic treatment, intravenous omeprazole significantly reduces the risk of rebleeding in patients with peptic ulcers at 3, 7, and 30 days Original...

The HMPS I: Adverse events in patients and negligence [Classics Series]

Image: PD 1. It was found that adverse events occurred in 3.7% of hospitalizations. 2. Approximately 27.6% of adverse events occurring in hospital were attributed to negligence. Study...

The HMPS II: Characterizing adverse events in hospitalized patients [Classics Series]

Image: PD 1. Drug-related complications were the most common type of adverse event in hospitalized patients. 2. Adverse events due to negligence in hospitalized patients were more...

The NASCET: Carotid endarterectomy for symptomatic stenosis [Classics Series]

Image: PD 1. Carotid endarterectomy, in addition to medical therapy, significantly reduces risk of major and fatal stroke in patients with symptomatic, high-grade (70-99%) carotid...

The EVAR I trial: Endovascular vs. open abdominal aortic aneurysm repair [Classics Series]

Image: PD 1. The EVAR I trial compared the safety and efficacy of endovascular and open abdominal aortic aneurysm repair 2. There were no significant differences...

The EVAR II trial: Endovascular approach when unfit for open aortic aneurysm repair [Classics...

Image: PD 1. The EVAR II trial compared endovascular abdominal aortic aneurysm repair with no intervention in patients unsuitable for the open procedure. 2. There were...
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