• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Cardiology

Coronary microvascular dysfunction demonstrating improvement after surgery for inflammatory bowel disease

byDavy LauandAlex Chan
May 6, 2021
in Cardiology, Chronic Disease, Gastroenterology, Surgery
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Inflammatory bowel disease (IBD) is associated with increased risk of coronary microvascular dysfunction (CMD).

2. Surgical intestinal resection in IBD patients improved coronary flow velocity reserve (CFVR), a measure of CMD.

Evidence Rating Level: 2 (Good)

Inflammatory bowel diseases (IBDs) include conditions such as Crohn Disease (CD) and Ulcerative Colitis (UC). They are characterized by acute and chronic inflammation of the gastrointestinal system, which can cause harm to the intestinal microvascular system and cardiovascular system. IBD was previously shown to be associated with reduced coronary flow velocity reserve (CFVR), a measure for coronary microvascular dysfunction (CMD). The current prospective study examined the extent of CMD in IBD patients, and the effect of surgical intestinal resection on coronary flow velocity (CFV) and CFVR. The study population consisted of 37 patients with IBD (aged 44±15), and 30 control patients (aged 46±12) with similar risk factors for coronary artery disease. The CFVR was measured with Doppler echocardiography, at rest and in hyperemia (during an infusion of ATP). For IBD patients, the CFVR was measured 1-5 days before and 3-6 months after surgical resection. The results found that 38% of IBD patients had CMD, whereas 0% of controls had CMD. At baseline, the CFVR was significantly less in IBD patients than in controls (for CD: 2.92±1.03, p < 0.05; and for UC: 2.99±0.65, p < 0.05). After surgery, coronary flow velocity was not significantly altered in IBD patients without CMD, whereas for those with CMD, the resting CFV was reduced (-19%±25%) and hyperemic CFV ameliorated (21%±34%). As well, CFVR was significantly improved in IBD patients both with and without CMD, though the extent of improvement was greater in those with CMD (interaction effect p < 0.001). The study showed that IBD is associated with greater risk of damage to the coronary arteries, and surgical resection may improve microvascular function.

Click to read the study in JAHA

Image: PD

©2021 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

RELATED REPORTS

Operating the day after performing surgery the previous night not associated with adverse patient outcomes

2 Minute Medicine Rewind May 22nd, 2022

Associations remain inconclusive between religiosity and spirituality on medication adherence in cardiovascular disease

Tags: cardiologyIBDSurgery
Previous Post

#VisualAbstract: ChAdOx1 nCov-19 AstraZeneca COVID-19 vaccine not effective against B.1.351 variant

Next Post

#VisualAbstract: Avelumab does not improve outcomes in patients receiving chemoradiotherapy for squamous cell carcinomas of the head and neck

RelatedReports

Quick Take: Intravenous patient-controlled analgesia versus thoracic epidural analgesia after open liver surgery
Public Health

Operating the day after performing surgery the previous night not associated with adverse patient outcomes

May 24, 2022
Weekly Rewinds

2 Minute Medicine Rewind May 22nd, 2022

May 23, 2022
Cardiology

Associations remain inconclusive between religiosity and spirituality on medication adherence in cardiovascular disease

May 16, 2022
Image-guided percutaneous drainage of pericardial effusions is safe and effective
Weekly Rewinds

2 Minute Medicine Rewind, May 16

May 16, 2022
Next Post
#VisualAbstract: Pembrolizumab improves long-term survival in patients with stage III melanoma

#VisualAbstract: Avelumab does not improve outcomes in patients receiving chemoradiotherapy for squamous cell carcinomas of the head and neck

High schoolers use e-cigarettes to vaporize cannabis

Substance use among hospitalized adolescents infrequently documented in electronic health record

Mental retardation associated with IVF treatment

No difference in live birth rates between intracytoplasmic sperm injection and conventional in-vitro fertilization for couples with non-male factor infertility

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

Get 2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Alzheimer disease in individuals with Down syndrome has similar variability in age of onset and mortality rate as autosomal dominant forms
  • #VisualAbstract: Ruxolitinib shows long-term safety and efficacy in inadequately controlled polycythaemia vera without splenomegaly
  • Wellness Check: Sleep
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.