• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Chronic Disease

Diabetic foot ulcers associated with worsening cognitive decline

byDeepti Shroff KarhadeandDavid Wang
May 21, 2016
in Chronic Disease, Endocrinology, Neurology
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

 

1. In a case-control study of approximately 200 patients with type 2 diabetes mellitus (T2DM), patients with diabetic foot ulcers were significantly associated with lower cognitive scores compared to T2DM controls

Evidence Rating Level: 3 (Average)       

Study Rundown: Diabetic foot ulcers are associated with significant morbidity and mortality in patients with T2DM, accounting for approximately 66% of non-traumatic amputations in the United States annually. The presence of ulcers increases the self-care burden on the part of the patient, and also requires that the patient has sufficient cognitive demands to understand and execute medical recommendations. The purpose of this study was to compare the cognitive profiles of patients with diabetic foot ulcers with patients with T2DM without foot ulcers. The study performed neurocognitive evaluations of T2DM patients with foot ulcers and matched T2DM controls. At the conclusion of the study, patients with foot ulcers demonstrated significantly decreased scores across all cognitive domains tested compared to controls and demonstrated significant decline from their estimated pre-morbid cognition. This was one of the first studies to examine cognitive status in this patient population and suggests that patients with diabetic foot ulcers face larger challenges to self-care while possessing less cognitive resources than control subjects. However, the study is limited by the cross-sectional design, which limits the assessment of causality between diabetic foot ulcers and cognitive decline.

Click to read the study in Diabetes Care

Relevant Reading: The relationship between cognitive impairment and diabetes self-management in a population-based community sample of older adults with Type 2 diabetes

In-Depth [case-control study]: Patients with T2DM and diabetic foot ulcers were recruited from in-hospital orthopedic departments and from diabetic foot clinics across two hospitals in Israel. Key exclusion criteria includes hepatic or renal failure, as well as patients with any visual, hearing, or cognitive impairment that could affect the neuropsychological testing. Cognitive testing assessed Glasgow Coma Scale, memory, attention, concentration, psychomotor efficiency, reaction time, executive function, and pre-morbid cognitive abilities. Overall, 99 patients with diabetic foot ulcers and 95 patients with T2DM without foot ulcers (matched for diabetes duration and gender) were recruited. At the conclusion of the trial, diabetic patients with foot ulcers had significantly lower cognitive scores than those without foot ulcers, in the cognitive domains for memory, reaction time, attention, executive function, psychomotor ability (p < 0.001). Additionally, patients with foot ulcers had a significantly higher difference between pre-morbid and current cognitive abilities compared to the patient population without foot ulcers.

RELATED REPORTS

Vitamin D effective in preventing the progression of pre-diabetes to diabetes

Dapagliflozin reduces the risk of hospitalization in patients with chronic kidney disease

SGLT2 inhibitors reduce the risk of kidney disease in patients with and without diabetes

Image: PD

©2015 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: cognitive declinediabetic foot ulcersType 2 Diabetes Mellitus
Previous Post

Pediatric DKA associated with recent acute care visits

Next Post

Misperceptions about prognosis among surrogates of critically ill patients

RelatedReports

Vitamin deficiency may persist after Omega-loop gastric bypass
Cardiology

Vitamin D effective in preventing the progression of pre-diabetes to diabetes

February 14, 2023
Solitary kidney not associated with contrast-induced nephropathy
Chronic Disease

Dapagliflozin reduces the risk of hospitalization in patients with chronic kidney disease

December 26, 2022
Tenofovir disoprovil fumarate HIV prophylaxis linked with minimal kidney impact
Chronic Disease

SGLT2 inhibitors reduce the risk of kidney disease in patients with and without diabetes

November 30, 2022
Parental nonmedical prescription opioid use linked to adolescent use
Chronic Disease

Combination therapy more effective than monotherapy for diabetic peripheral neuropathic pain

September 6, 2022
Next Post
Corticosteroids improve outcomes in treatment of community-acquired pneumonia

Misperceptions about prognosis among surrogates of critically ill patients

Pulmonary MRI with ultrashort echo time is comparable to pulmonary CT

Endobronchial coiling for emphysema associated with moderate improvement in exercise tolerance

Postextubation administration of high-flow oxygen leads to reduced reintubation and respiratory failure

Aspirin does not decrease the incidence of ARDS in at-risk patients

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Exhaled volatile organic compounds predict bronchopulmonary dysplasia in preterm infants
  • Wellness Check: Mental Health
  • SAR-CoV-2 infection during pregnancy may lead to adverse neurodevelopmental outcomes in male offspring
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

Want more physician-written
medical news?

Join over 10 million yearly readers and numerous companies. For healthcare professionals
and the public.

Subscribe for free today!

Subscription options