• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Chronic Disease

HbA1c overestimates mean glucose in black persons compared with whites

byCaitlyn HuiandDeepti Shroff Karhade
June 14, 2017
in Chronic Disease, Endocrinology, Public Health
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Mean glucose concentration was significantly lower in black compared to white patients; however, HbA1c levels in black patients were higher than white patients.

2. Differences in glucose concentration with HbA1c may be attributed to racial differences in glycation of hemoglobin.

Evidence Rating Level: 2 (Good)

Study Rundown: Hemoglobin A1c (HbA1c) is used in standard clinical practice as a marker for glycemic control in diabetes patients. The results of this test are important, as they help guide diabetes management—particularly with respect to the use of drugs—as well as assess risk for diabetic complications. While higher HbA1c levels are usually observed in black patients, it is unclear as to whether this difference is due to differences in glycemic control or racial differences in the glycation of hemoglobin. Considering this debate, the authors of the study aimed to determine whether there is a racial difference in mean glucose and HbA1c for black patients compared to white patients. The main limitation of the study was that the results had to be interpreted in light of the inclusion criteria. Specifically, there were too few participants with HbA1c levels less than 6.5% to generalize the results to those individuals. Overall, the results of this study suggest that, on average, HbA1c levels overestimate mean glucose in black persons compared with whites. This difference may be due to racial differences in glycation of hemoglobin.

Click to read the study in the Annals of Internal Medicine

Relevant Reading: Racial and Ethnic Differences in the Relationship between HbA1c and Blood Glucose: Implications for the Diagnosis of Diabetes

In-Depth [prospective cohort]: In this prospective, 12-week observational study, 104 black patients and 104 white patients were included from 10 different diabetes centres in the United States. All study participants had type 1 diabetes with an HbA1c level of 6.0% to 12.0%. The study endpoints consisted of mean glucose concentration, glycated albumin, and fructosamine values. Generally, HbA1c levels were found to overestimate glucose concentration in black patients compared to white patients. Specifically, HbA1c values in black patients were 0.4 percentage points (95%CI 0.2 to 0.6 percentage point) higher than those in white persons for a given mean glucose concentration. In contrast, while glycated albumin and fructosamine values were highly correlated with HbA1c, no clinically significant racial differences were found in terms of their relationship with mean glucose concentration (p > 0.20 for each comparison).

RELATED REPORTS

Faricimab may improve visual acuity in patients with diabetic macular edema

Supplementation of tirzepatide for type 2 diabetics on basal insulin improved glycemic control compared to placebo

Tirzepatide is superior to insulin glargine for management of type 2 diabetes and elevated cardiovascular risk

Image: PD

©2017 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: diabetes mellitushba1c
Previous Post

New standardized score identifies patients who should be treated with shorter duration dual-antiplatelet therapy

Next Post

Parenting intervention in African American youth yields lower cotinine levels

RelatedReports

Blindness and visual impairment decreasing worldwide
Chronic Disease

Faricimab may improve visual acuity in patients with diabetic macular edema

March 8, 2022
Insulin costs rose exponentially, regardless of formulation or patent
Cardiology

Supplementation of tirzepatide for type 2 diabetics on basal insulin improved glycemic control compared to placebo

February 9, 2022
Cardiology

Tirzepatide is superior to insulin glargine for management of type 2 diabetes and elevated cardiovascular risk

January 11, 2022
#VisualAbstract: Lowering systolic blood pressure with antihypertensives may reduce new-onset type 2 diabetes
StudyGraphics

#VisualAbstract: Lowering systolic blood pressure with antihypertensives may reduce new-onset type 2 diabetes

December 2, 2021
Next Post
Five risk factors linked to half of preventable cardiovascular deaths

Parenting intervention in African American youth yields lower cotinine levels

Characteristic differences between young children and adolescents who die by suicide

Inverse relationship between level of education and risk of cardiovascular disease

Food environment associated with gestational diabetes

Self-monitoring of glucose in non-insulin dependent diabetics not linked to improved control

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

Get 2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Wellness Check: Mental Health
  • #VisualAbstract: Addition of elotuzumab to lenalidomide and dexamethasone did not significantly improve survival outcomes in newly diagnosed, transplant-ineligible multiple myeloma
  • #VisualAbstract: Pretreatment with radiotherapy and two cycles of concurrent cisplatin may reduce toxicity in locally advanced nasopharyngeal carcinoma
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.