• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Cardiology

Higher 24-hour and nighttime blood pressure readings associated with increased risk of death and poor cardiovascular outcomes

byJason Nam, MDandDaniel Fisher
August 9, 2019
in Cardiology, Chronic Disease, Public Health
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. In this prospective cohort study, higher 24-hour and nighttime blood pressure measurements were significantly associated with greater risks of death and a composite cardiovascular (CV) outcome.

2. 24-hour and nighttime blood pressure may be considered optimal measurements for estimating CV risk however, there was only a very modest improvement in prediction of risk when added to standard blood pressure indexes taken in ambulatory settings.

Evidence Rating Level: 2 (Good)

Study Rundown: Ambulatory blood pressure (BP) readings are recommended by most national guidelines for hypertension assessments. However, recent studies suggest that nighttime measurements may be more predictive of poor outcomes in hypertension, and it is unclear if BP readings at night or over 24 hours are similar in terms of assessing risk. In this prospective cohort study, higher 24-hour and nighttime blood pressure measurements were significantly associated with greater risks of death and a composite cardiovascular (CV) outcome, even after adjusting for other office-based or ambulatory blood pressure measurements. 24-hour and nighttime blood pressure were found to be optimal measurements for estimating CV risk, however, there was only a very modest improvement in prediction of risk when added to standard blood pressure indexes.

Though this study suggests small improvements in hypertension risk assessment with nighttime and 24-hour BP index, it has some limitations. Antihypertensive drug treatment was only recorded at baseline and could therefore not be adjusted for as a time-dependent covariable. There also might be misclassification bias in the assessment of the CV study end points.

Click to read the study in JAMA

RELATED REPORTS

Anal cancer screening cost-effective for men who have sex with men with human immunodeficiency virus aged above 35 years

Semaglutide may improve cardiovascular outcomes versus empagliflozin in patients with diabetes

Hypotension- and hypertension-avoidance strategies may yield similar neurocognitive outcomes following noncardiac surgery

Relevant Reading: Night-time home versus ambulatory blood pressure in determining target organ damage.

In-Depth [prospective cohort]: 11,135 adults were recruited across many countries with a median follow-up of 13.8 years. The primary end points were total mortality and a composite CV event consisting of CV mortality combined with nonfatal coronary events, heart failure, and stroke. Secondary end points included CV mortality and a variety of other coronary events. Both primary end points were significantly associated with all single systolic BP indexes (p < .001). For nighttime systolic BP level, the hazard ratio (HR) for total mortality was 1.23 (CI95 1.17 to 1.28) and 1.36 for CV events (CI95 1.30 to 1.43). For the 24-hour systolic BP level, the HR for total mortality was 1.22 (CI95 1.16 to 1.28) and 1.45 for CV events (CI95 1.37 to 1.54). With adjustment for any of the other systolic BP indexes, the associations of nighttime and 24-hour systolic BP with the primary outcomes remained statistically significant (HRs ranging from 1.17; CI95 1.10 to 1.25; to 1.87; CI95 1.62 to 2.16). In models including both 24-hour and nighttime BP measures, secondary outcomes were significantly associated with nighttime BP. HRs for systolic and diastolic 24-hour BP was 1.36 (CI95 1.14 to 1.63) and 1.24 (CI95 1.06 to 1.44), respectively.

Image: PD

©2019 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: antihypertensivesblood pressurecardiovascular riskhypertensionmortality
Previous Post

Quick Take: Prevalence of aspirin use for primary prevention of cardiovascular disease in the United States

Next Post

Quick Take: Overall survival with ribociclib plus endocrine therapy in breast cancer

RelatedReports

Government-funded initiatives provide important supports to low-income HIV patients
Infectious Disease

Anal cancer screening cost-effective for men who have sex with men with human immunodeficiency virus aged above 35 years

June 16, 2025
Compliance-linked incentives increase infant immunizations rates in rural India
Endocrinology

Semaglutide may improve cardiovascular outcomes versus empagliflozin in patients with diabetes

June 16, 2025
Prevalence of hypertension among adolescents varies by race and BMI
Chronic Disease

Hypotension- and hypertension-avoidance strategies may yield similar neurocognitive outcomes following noncardiac surgery

June 14, 2025
Downward trend in mortality rate for antineutrophil cytoplasmic autoantibody-associated vasculitis
AI Roundup

Becton Dickinson Unveils Artificial Intelligence Powered Monitor for Surgery

May 28, 2025
Next Post
Age and breast cancer risk factors associated with false-positive mammography results

Quick Take: Overall survival with ribociclib plus endocrine therapy in breast cancer

#VisualAbstract: Burden and Causes of Hospital Admissions in Heart Failure During the Last Year of Life

#VisualAbstract: Burden and Causes of Hospital Admissions in Heart Failure During the Last Year of Life

#Visual Abstract: Adolescent Mental Health Program Components and Behavior Risk Reduction: A Meta-analysis

#Visual Abstract: Adolescent Mental Health Program Components and Behavior Risk Reduction: A Meta-analysis

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Early screening for emotional and cognitive issues may improve psychiatric outcomes for stroke patients
  • Artificial intelligence may assist in early detection of decreased ejection fraction on echocardiograms
  • #VisualAbstract: Tarlatamab Improves Survival in Small-Cell Lung Cancer after Platinum-Based Chemotherapy
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.