Tag: hypertension

1. A 6% risk reduction for developing hypertension was associated with a 1-point improvement in Life’s Simple 7 score, a metric for cardiovascular health. Evidence Rating Level: 2 (Good) Hypertension is a condition that affects roughly half of the adult US population, and is a known risk factor for cardiovascular disease...

1. A workplace intervention that determined employees’ body age was found to decrease body age score, reduce smoking habits, lower risk factors for chronic disease, and lower rates for metabolic syndrome. Evidence Rating Level: 2 (Good) As life expectancy in western countries continues to rise, the legislated retirement age is also...

1. A 6% risk reduction for developing hypertension was associated with a 1-point improvement in Life’s Simple 7 score, a metric for cardiovascular health. Evidence Rating Level: 2 (Good) Hypertension is a condition that affects roughly half of the adult US population, and is a known risk factor for cardiovascular disease...

1. In this randomized clinical trial, patients who received bariatric surgery were nearly 7 times more likely to achieve at least 30% reduction in the total number of hypertensive medications and nearly 20 times more likely to achieve blood pressure control without medications compared to those who did not...

1. In a large, national sample, approximately 37.1% of patients with stroke history had uncontrolled blood pressure. 2. Most patients on medication were taking angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, diuretics, or calcium channel blockers. Evidence Rating Level: 2 (Good) Stroke is ranked as a leading cause of mortality and disability in...

Characteristics and Strength of Evidence of COVID-19 Studies Registered on ClinicalTrials.gov 1. While there has been a rise in clinical trials on COVID-19, a large proportion of these studies are expected to yield low levels of evidence. Evidence Rating Level: 3 (Average) The rapid and widespread transmission of coronavirus disease 2019 (COVID-19)...

1. Incidence of intracerebral hemorrhage in older patients has increased since 1948. 2. Hypertension and statin use are both associated with intracerebral hemorrhage. Evidence Rating Level: 3 (Average) Study Rundown: Of all stroke types, intracerebral hemorrhage (ICH) possesses the highest mortality rate and is the greatest cause of disability. While stroke incidence...

1. Amongst the five examined classes of antihypertensive medications (ACE Inhibitors, ARBs, beta blockers, calcium-channel blockers, and thiazide diuretics), none were associated with a substantial increase in likelihood of COVID-19. Evidence Rating: 2 (Good) Infection of host cells by SARS-CoV-2 is mediated via an interaction with membrane-bound angiotensin-converting enzyme (ACE) 2,...

Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial 1. Adults with severe COVID-19 treated with remdesivir had numerically faster time to clinical improvement compared to controls, but the difference was not statistically significant Evidence Rating: 1 (Excellent) Months into declaration of COVID-19 as a pandemic, there still remains...

1. While chlorthalidone is the recommended thiazide diuretic treatment for hypertension, it has no added benefits compared to hydrochlorothiazide and has significantly worse safety profile. Evidence Rating Level: 1 (Excellent) The American College of Cardiology/American Heart Association hypertension guideline reported in 2017 that the recommended thiazide diuretic treatment for hypertension is currently...