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Home All Specialties Chronic Disease

An online program combining mindfulness strategies with exercise may be effective for patients with chronic pain

byPaary BalakumarandSimon Pan
January 13, 2026
in Chronic Disease, Lifestyle, Psychiatry
Reading Time: 2 mins read
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1. An online program combining mindfulness-based stress reduction and exercise, as well as the online self-management guide, both led to modest long-term improvements in pain, function, and psychological well-being, with no significant differences between the two.

Evidence Rating Level: 1 (Excellent)

This exploratory one-year follow-up of the mindfulness combined with exercise delivered online (MOVE) feasibility randomized controlled trial investigated the long-term impact of an online program combining Mindfulness-Based Stress Reduction (MBSR) and exercise for individuals with chronic pain. 96 participants were randomized to either the MOVE intervention or an online self-management (SM) guide. The study assessed 14 patient-reported outcome measures (PROMs) at baseline, post-intervention, 3 months, and one year. At one-year follow-up, 48 participants completed assessments. Results showed small, non-significant between-group differences, with slight advantages for the MOVE group in depression (PHQ-9) and mental health-related quality of life (SF-36 MCS), while nine measures favored the SM group. Within-group trends indicated modest improvements in pain, function, and psychological measures across both groups. Notably, 63% of the MOVE group versus 44% of the SM group reported subjective improvement on the Patient Global Impression of Change scale. The study concludes that both online formats are feasible and acceptable, though a fully powered RCT is needed to determine the true efficacy of combined MBSR and exercise interventions in chronic pain management.

Click here to read this study in PLOS One

Image: PD

©2025 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc. 

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