Tag: hemoglobin

1. Children with sickle cell disease who received the maximum tolerated dose of hydroxyurea had higher concentrations of hemoglobin and fetal hemoglobin compared to those who received the fixed standard dose. 2. Patients in the dose escalation group also had fewer adverse events and required fewer key medical interventions than...
1. In this secondary analysis of data from the CANTOS trial in 2017, canakinumab significantly reduced the incidence of anemia in patients with a history of myocardial infarction. 2. Among participants with baseline anemia, those who received canakinumab had significantly higher hemoglobin levels versus placebo. Evidence Rating Level: 3 (Average) Study Rundown:...
1. Maternal hemoglobin levels were measured at 2 antenatal visits and delivery, while their infants were followed 1 year later and assessed for gross motor (GM) functions. Prevalence of maternal anemia fell from 67% in the first antenatal visit to 38.4% at the time of delivery. 2. GM scores peaked...
Image: CC/L. academia 1. In patients with anemia and chronic kidney disease, treating with epoetin alfa to a lower hemoglobin target was associated with significantly reduced incidence of the composite event (death, MI, hospitalization for CHF, and stroke). 2. Achieving the lower hemoglobin target required significantly lower doses of epoetin alfa. Study Rundown:...
Image: PD 1. Daily iron supplementation in 2- to 5-year-olds increases hemoglobin and ferritin levels, though there is insufficient data to infer impact on iron deficiency anemia.  2. Supplementation has no effect on physical growth or morbidity from infectious causes. 3. Further data are needed to assess effects of daily iron supplementation...