Dazukibart is effective in reducing disease activity in adults with refractory dermatomyositis
1. CDASI-A score at 12 weeks was significantly lower in dazukibart 600 mg versus placebo, suggesting reduced morbidity. 2. Treatment-related ...
Tag: monoclonal antibody
Mirikizumab is safe and effective in patients with moderate-to-severe Crohn’s disease
1. The composite of patient-reported clinical response and endoscopic response was significantly greater in mirikizumab versus placebo. 2. Clinical remission ...
Denosumab may increase risk of major adverse cardiovascular events but reduce fracture risk in patients receiving dialysis
1. In this target trial emulation study, denosumab was associated with an increased risk of major adverse cardiovascular events compared ...
Incyte: Monjuvi improves survival in patients with relapsed or refractory follicular lymphoma
The addition of Monjuvi to standard-of-care therapy reduced the risk of disease progression, relapse, or death in patients with relapsed/refractory ...
AbbVie’s novel epkinly results in meaningful treatment response in patients with treatment-refractory lymphoma
Epkinly showed an overall response rate of 82% with 62.5% of patients achieving complete response. 65% of patients had grade ...
Infusion with a monoclonal antibody decreases migraine frequency
1. In this randomized controlled trial, in patients diagnosed with migraine, it was found that administration of a monoclonal antibody ...
#VisualAbstract: Lu AG09222, a Monoclonal Antibody Targeting Pituitary Adenylate Cyclase-Activating Polypeptide, Reduced Migraine Episodes
Click here to read this study in NEJM. ©2024 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced ...
Eli Lilly: Kisunla was shown to reduce symptoms and slow disease progression in adults with early symptomatic Alzheimer’s disease.
Compared to the placebo, patients treated with Kisunla had a 35% slower cognitive and functional decline at 18 months of ...
#VisualAbstract: Benralizumab reduced histological eosinophil presence without improving symptoms of eosinophilic esophagitis
Click here to read this study in NEJM. ©2024 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced ...
Monoclonal antibody CIS43LS efficacious in preventing malaria in Mali
1. The monoclonal antibody CIS43LS was associated with dose-dependent protection against malaria infection in adults in Mali. 2. CIS43LS had ...