Tag: neuropathy

1. A shortened course of oxaliplatin-based adjuvant chemotherapy for stage III colon cancer was associated with decreased peripheral sensory neuropathy without compromising effectiveness. Evidence Rating Level: 1 (Excellent) FOLFOX4 regimen, which includes oxaliplatin, has proven efficacy in both the metastatic colorectal cancer setting and the adjuvant setting for resected stage III...

Efficacy and Long-term Peripheral Sensory Neuropathy of 3 vs 6 Months of Oxaliplatin-Based Adjuvant Chemotherapy for Colon Cancer: The ACHIEVE Phase 3 Randomized Clinical Trial 1. A shortened course of oxaliplatin-based adjuvant chemotherapy for stage III colon cancer was associated with decreased peripheral sensory neuropathy without compromising effectiveness. Evidence Rating Level:...

1. In this prospective cohort study from Brazil, most patients admitted with new parainfectious/neuroinflammatory conditions including Guillain-Barré syndrome (GBS), meningoencephalitis, or transverse myelitis had molecular or serologic evidence of recent Zika Virus (ZIKV) infection. 2. Rates of admission for neuroinflammatory conditions were higher in Brazil during the study period than...

1. In a prospective study of patients receiving neurotoxic chemotherapy, those who suffered from symptoms of chemotherapy-induced peripheral neuropathy (CIPN) were more than twice as likely to have a fall or near fall during a two-month follow up. 2. The study had short term follow up and a small sample...

Image: PD 1. Painful peripheral neuropathy is a common side effect of modern chemotherapy regimens. 2. The serotonin and norepinephrine reuptake inhibitor duloxetine significantly reduces neuropathic pain and improves quality of life in patients receiving chemotherapy.  Study Rundown: Peripheral neuropathy is a common side effect of chemotherapy that has proven extremely difficult...