Digitoxin improves outcomes in heart failure with reduced ejection fraction
1. Among patients with symptomatic chronic heart failure already on guideline-directed medical therapy (GDMT), digitoxin lowered all-cause mortality and hospital ...
Tag: preventative medicine
Low-dose yellow fever vaccine non-inferior to standard dose
1. This randomized controlled trial conducted in Kenya and Uganda assessed whether fractional doses of the 17D-204 yellow fever vaccine ...
Levofloxacin shows limited efficacy in preventing multidrug-resistant tuberculosis
1. In this randomized controlled trial, daily levofloxacin treatment in patients with multidrug-resistant (MDR) or rifampicin-resistant Mycobacterium tuberculosis did not ...
Fractional dosing of pneumococcal conjugate vaccine noninferior to full dosing schedule
1. In this randomized non-inferiority trial, 40% of a full dose of the 13-valent pneumococcal conjugate vaccine (PCV13) was noninferior ...
Reduced pneumococcal vaccine schedules non-inferior to WHO recommendations
1. In this cluster-randomized controlled trial, it was found that a pneumococcal conjugate vaccine (PCV) schedule involving a single primary ...
![Maternal cell-free DNA sequencing superior to standard aneuploidy screening [CARE Study]](https://www.2minutemedicine.com/wp-content/uploads/2014/02/47-karyotype-350x250.jpg)
Australian couple-based genetic screening program feasible and accepted
1. In this prospective cohort study, genetic screening among Australian reproductive couples was widely accepted and associated with low decisional ...
MRI-informed biopsy recommendation reduces overdiagnosis in prostate cancer screening
1. In this randomized controlled trial of men aged 50 to 60, forgoing prostate biopsies in those with elevated PSA ...
Communities That HEAL intervention does not reduce opioid-related mortality
1. In this cluster-randomized controlled trial, in communities with a high rate of opioid-related overdoses, the implementation of the Communities ...
Twice-yearly azithromycin distribution reduces childhood mortality in rural Niger
1. In this randomized cluster trial, twice-yearly azithromycin distribution reduced all-cause childhood mortality among children aged one to 59 months ...
![Active smoking cessation intervention may provide tangible results [Project CLIQ]](https://www.2minutemedicine.com/wp-content/uploads/2014/12/smoking-e1418644951268-350x250.jpg)
Including e-cigarettes in smoking cessation counseling increases tobacco abstinence
1. In this randomized controlled trial, participants who received free e-cigarettes in addition to counseling had greater continuous abstinence from ...
