• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Cardiology

Elevated systolic blood pressure is associated with left ventricular remodelling in adults born preterm

byDavy LauandAlex Chan
May 12, 2022
in Cardiology, Chronic Disease, Obstetrics
Reading Time: 3 mins read
0
Share on FacebookShare on Twitter

1. In pre-term adults, an elevated systolic blood pressure was associated with left ventricular (LV) remodelling, including a greater LV mass index and greater LV mass to end-diastolic volume ratio.

2. The association between high blood pressure and LV remodelling was greater in adults born very pre-term (<32 weeks gestation) compared to those born moderately pre-term.

Evidence Rating Level: 2 (Good)

Study rundown: The link between preterm birth and an elevated risk of heart failure or ischemic heart disease is well established. This may be because the hearts of preterm born individuals are associated with cardiac remodelling, resulting in smaller internal left ventricle (LV) size and LV hypertrophy. As well, preterm individuals tend to experience higher blood pressure (BP), and are at greater risk of hypertension. The current study sought to investigate the association between systolic BP and LV structure/function, and whether this association varies by degree of prematurity. Blood pressure measurements and cardiac magnetic resonance imaging was done on a cohort of 468 adults: 51.5% women, >95% Caucasian, and 42.7% born preterm. As well, more than 25% were hypertensive, thereby addressing a limitation of previous studies (where inadequate numbers of hypertensive patients were enrolled). Overall, the study found a link between higher systolic BP and cardiac remodelling, represented by a greater LV mass index and greater LV mass to end-diastolic volume ratio. Furthermore, this association was more prominent in very preterm-born individuals (<32 weeks gestation) compared to moderately preterm individuals.

Click here to read the article in JAMA Cardiology

Relevant Reading:  Preterm Heart in Adult Life: Cardiovascular Magnetic Resonance Reveals Distinct Differences in Left Ventricular Mass, Geometry, and Function

RELATED REPORTS

#VisualAbstract: Obicetrapib Reduced LDL Cholesterol in Patients at High Cardiovascular Risk

Living in a marginalized neighbourhood is associated with worse outcomes in patients with myocardial infarction

Mazdutide significantly reduces weight in adults with overweight or obesity

In-Depth [prospective cohort]: All patients were adults aged 18 to 40 years old, with a BMI of less than 40, and with no history of cardiac and cerebrovascular disease, or treatment for hypertension. Of the 200 patients born preterm, 52.5% were moderately preterm (32-36 weeks gestation), 37.0% were very preterm (28-31 weeks), and 10.5% were extremely preterm (<28 weeks). Cardiac magnetic resonance imaging was done to analyze the volume, mass, and dimensions of the left ventricle. The results showed that adults born pre-term had reduced LV function, smaller LV volume, and higher LV mass index, compared to term-born individuals, regardless of hypertension status. For LV mass index, very and extremely pre-term born adults had a 2.5 times greater LV mass index for every 1-mm Hg increase in systolic BP (0.394 g/m2 in pre-term, 0.157 g/m2 in term-born; p < 0.001). This was 1.6 times greater for moderately pre-term born adults (0.250 g/m2 vs 0.157 g/m2; p < 0.001). Additionally, the LV mass to end-diastolic volume ratio was 3.4 times greater for every 1-mm Hg increase in systolic BP, when comparing very and extremely pre-term individuals to moderately pre-term (3.56*10-3 vs 1.04*10-3 g/mL, p < 0.001), and 3.3 times greater when comparing very and extremely pre-term to term-born individuals (3.56*10-3 vs 1.08*10-3 g/mL, p < 0.001). Overall, elevated systolic blood pressure was associated with left ventricular remodelling, and to a greater extent in individuals born before 32 weeks gestation.

Image: PD

©2021 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: cardiologyhypertension
Previous Post

2 Minute Medicine Rewind May 17, 2021

Next Post

Maternal weight gain and pregnancy outcomes in twin gestations

RelatedReports

#VisualAbstract: Obicetrapib Reduced LDL Cholesterol in Patients at High Cardiovascular Risk
StudyGraphics

#VisualAbstract: Obicetrapib Reduced LDL Cholesterol in Patients at High Cardiovascular Risk

July 15, 2025
Cardiology

Living in a marginalized neighbourhood is associated with worse outcomes in patients with myocardial infarction

July 12, 2025
Increasing maternal BMI linked to higher risk of cerebral palsy
Cardiology

Mazdutide significantly reduces weight in adults with overweight or obesity

July 11, 2025
Cerebral protection device effective in patients undergoing transcatheter aortic valve implantation
Cardiology

Cerebral embolic protection does not decrease stroke incidence in TAVI patients

July 8, 2025
Next Post
Increased severe maternal morbidity with multiple gestation pregnancies

Maternal weight gain and pregnancy outcomes in twin gestations

Higher plasma levels of omega-3 fatty acids not associated with worse cardiovascular outcomes compared to corn oil placebo

Reinnervation of cardiac infarcts decreases subsequent arrhythmia incidence [PreClinical]

Carriers of truncated variants in filamin C with left ventricular systolic dysfunction associated with increased frequency of cardiac adverse events

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • New-generation antiseizure medications are better tolerated for patients with epilepsy
  • #VisualAbstract: Insulin Efsitora is Noninferior to Insulin Glargine in Type 2 Diabetes without Previous Insulin Therapy
  • Thrombolysis-to-puncture time greater than 70 minutes decreases odds of successful thrombectomy
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.