• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Emergency

Pathological computed tomography features associated with adverse outcomes after mild traumatic brain injury

byDavy LauandAlex Chan
July 29, 2021
in Emergency, Neurology
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

RELATED REPORTS

Lecanemab may slow cognitive decline in early Alzheimer’s disease

Ultraprocessed food intake is associated with cognitive decline in geriatric populations

2 Minute Medicine Rewind December 12, 2022

1. For mild traumatic brain injury, various pathological findings were associated with different prognostic implications for mild traumatic brain injury up to 1 year. 

Evidence Rating Level: 2 (Good)

An acute traumatic brain injury (TBI) is characterized by various forms of intracranial hemorrhage observed on a computed tomography (CT) scan. The association between different findings on CT and prognosis has been researched extensively for moderate and severe TBI, but not for mild TBI. This is because impairments from mild TBI tend to be more subtle, thereby requiring larger study populations to make prognostic determinations. The current longitudinal study examined  mTBI patients at 18 American Level 1 trauma centres at 2 weeks, 3, 6, and 12 months after injury. These results were then externally validated with another longitudinal cohort of 2594 mTBI patients from 55 European trauma centres. Patients with mTBI were those with Glasgow Coma Scale scores of 13 to 15 upon presentation to the emergency department. The primary outcome was the Glasgow Outcome Scale-Extended (GOSE) score, an 8-point scale measuring global function after TBI: Incomplete recovery was defined as a GOSE score less than 8, and greater degrees of unfavourable outcomes was defined as a GOSE score less than 5. Three categories of CT findings emerged from cluster analysis: The first category consisted of contusion, subarachnoid hemorrhage (SAH), and subdural hematoma (SDH); the second consisted of intraventricular and petechial hemorrhage; and the third consisted of epidural hematoma. The results showed that the first cluster was strongly associated with incomplete recovery from 2 weeks to 12 months, with odds ratios ranging from 1.67 at 6 months (95% CI 128-2.17) to 2.22 at 2 weeks (95% CI 1.61-3.06). This cluster was also associated with greater degrees of unfavourable outcomes from 2 weeks to 12 months (OR 2.14, 95% CI 1.48-3.10 at 2 weeks; OR 3.23, 95% CI 1.59-6.58 at 12 months). The second cluster of CT features was significantly associated with unfavourable outcomes at 3, 6, and 12 months (OR 2.37, 95% CI 1.14-4.92 at 3 months; OR 3.47, 95% CI 1.66-7.26 at 12 months). Lastly, epidural hematoma was associated with incomplete recovery at the earlier time points (OR 3.08, 95% CI 1.27-7.49, p = 0.01 at 2 weeks; OR 2.33, 95% CI 1.28-4.24, p = 0.006 at 3 months). Overall, various pathological features on CT were associated with different prognostic outcomes for mild TBI, with recovery being impacted anywhere from 2 weeks to 12 months after injury.

Click to read the study in JAMA Neurology

Image: PD

©2021 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: neurologystroketbi
Previous Post

Short-term seizure prophylaxis maximizes quality-adjusted life-years in simulated spontaneous intracerebral hemorrhage patients

Next Post

Wellness Check: Exercise

RelatedReports

Free alternatives comparable to Mini-Mental State Examination
Chronic Disease

Lecanemab may slow cognitive decline in early Alzheimer’s disease

January 10, 2023
Dietary variety linked to greater increase in childhood BMI
Chronic Disease

Ultraprocessed food intake is associated with cognitive decline in geriatric populations

December 14, 2022
Eczema more prevalent among older adults than previously thought
Weekly Rewinds

2 Minute Medicine Rewind December 12, 2022

December 13, 2022
Population-based risk factors and geographical trends identified for vitiligo
Cardiology

The majority of FDA-approved drug trials recruit from low- and middle-income countries

December 9, 2022
Next Post
Few older adolescents meet recommended levels of physical activity

Wellness Check: Exercise

#VisualAbstract Cases of post-COVID-19 diffuse hair shedding may have a delayed presentation and be shorter in duration than typical acute telogen effluvium

#VisualAbstract Cases of post-COVID-19 diffuse hair shedding may have a delayed presentation and be shorter in duration than typical acute telogen effluvium

#VisualAbstract: Mixed vaccination with ChAdOx1-S followed by BNT162b2 induces a robust humoral immune response

#VisualAbstract: Mixed vaccination with ChAdOx1-S followed by BNT162b2 induces a robust humoral immune response

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Chronic obstructive pulmonary disease associated with worse postoperative outcomes
  • Empagliflozin use is associated with slower progression of chronic kidney disease
  • Diagnostic tool may help identify cerebral palsy regardless of encephalopathy features
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

Want more physician-written
medical news?

Join over 10 million yearly readers and numerous companies. For healthcare professionals
and the public.

Subscribe for free today!

Subscription options