Tag: blood transfusion

1. In African children with uncomplicated severe anemia, immediate blood transfusion did not notably alter patient mortality at 1- or 6-months post treatment compared to patients treated under current practice. 2. Rates of hospital readmission, serious adverse events, and hemoglobin recovery were similar between the two groups. Evidence Rating Level: 1...
1. In African children with uncomplicated severe anemia, immediate blood transfusion did not notably alter patient mortality at 1- or 6-months post treatment compared to patients treated under current practice. 2. Rates of hospital readmission, serious adverse events, and hemoglobin recovery were similar between the two groups. Evidence Rating Level: 1...
1. In this large retrospective cohort, there were no increases in mortality from red blood cell transfusions from female, previously pregnant, or sex-discordant donors. Evidence Rating Level: 2 (Good) Study Rundown: Recently, a few studies have suggested that blood donation from female donors, especially to male recipients, may result increased adverse...
1. This microsimulation study suggested that screening blood for Zika virus is only cost-effective during the high mosquito season in Puerto Rico. 2. The authors of the study did not identify any cost-effective screening policy for Zika virus in the 50 states. Evidence Rating Level: 2 (Good) Study Rundown: Zika is an...
1. The authors observed in this retrospective cohort study that transfusion rates decreased among patients from 2010 and 2014. 2. Paralleling decreasing transfusion rates, the authors observed a reduction in 6-month mortality rates among patients with moderate anemia from 2010 and 2014. Evidence Rating Level: 2 (Good) Study Rundown: Anemia is a...
1. In this retrospective analysis, there was a slight increase in male patient mortality per transfusion when receiving blood from an ever-pregnant donor compared to a male or never-pregnant female donor. 2. This association seemed to be strongest for recipients under 50 years of age. Evidence Rating Level: 3 (Average) Study Rundown:...
1. No significant differences in mortality were observed when comparing patients that received fresh versus stored blood. 2. Findings indicate that the current practice of storing RBCs for up to 42 days does not need to be changed.   Evidence Rating Level: 2 (Good) Study Rundown: The storage of red blood cells...
1. In a prospective cohort study of over 120 Jehovah’s Witnesses with lymphoma and multiple myeloma, high-dose chemotherapy (HDC), and autologous stem-cell transplantation (ASCT) without transfusion support was associated with relatively low mortality and morbidities. Evidence Rating Level: 3 (Average) Study Rundown: The standard of care for high risk or recurrent...