Tag: cardiac arrest

1. The proportion of out of hospital cardiac arrests (OHCAs) within all acute myocardial infarction (AMI) hospital admissions was higher at the start of the COVID-19 pandemic compared to before, by a difference of 2.0%. 2. The in-hospital mortality rate for OHCAs during COVID-19 was higher than before, by a...
Classics Series, Landmark Trials in Medicine
1. The POISE trial was a randomized controlled trial exploring the effect of perioperative beta-blockers on cardiac death, nonfatal myocardial infarctions, and nonfatal cardiac arrest. 2. Perioperative oral extended-release metoprolol was found to reduce the risk of nonfatal myocardial infarction, while increasing the risk of stroke and mortality when compared...
1. A 2-day course of amoxicillin-clavulanate and targeted temperature management of 32-34 degrees Celsius after cardiac arrest with shockable rhythm resulted in a lower incidence of early ventilator-associated pneumonia than the control group. 2. The intervention did not cause a significant decrease in the rate of late ventilator-associated pneumonia, number...
1. A 2-day course of amoxicillin-clavulanate and targeted temperature management of 32-34 degrees Celsius after cardiac arrest with shockable rhythm resulted in a lower incidence of early ventilator-associated pneumonia than the control group. 2. The intervention did not cause a significant decrease in the rate of late ventilator-associated pneumonia, number...
While it is known that suboptimal chest compressions are associated with worse outcomes after cardiac arrest, the optimal combination of chest compression rate (CCR) and chest compression depth (CCD), and whether this should be applied to all patients despite differences in age, sex, and presenting cardiac rhythm is unknown....
Pregnancy duration and endometrial cancer risk: nationwide cohort study Full-term pregnancies are strongly associated with a reduced risk of endometrial cancer. Whether this protective association is driven by fecundity, a specific process that occurs during pregnancy, or cumulative number of months pregnancy, however, is unknown. In this cohort study, 2,311,332...
1. In this randomized controlled trial, intra-cardiac arrest, trans-nasal evaporative cooling did not improve survival with good neurologic outcome at 90 days compared to standard systemic cooling in the ICU. 2. The time to core target temperature was shorter in the intra-nasal cooling group. Evidence Rating Level: 1 (Excellent) Study Rundown: There is...
1. In this randomized controlled trial, intra-cardiac arrest, trans-nasal evaporative cooling did not improve survival with good neurologic outcome at 90 days compared to standard systemic cooling in the ICU. 2. The time to core target temperature was shorter in the intra-nasal cooling group. Evidence Rating Level: 1 (Excellent) Study Rundown: There...
1. In an American, randomized controlled trial, supraglottic airway (SGA) resuscitation was associated with marginally better neurological outcomes and 72-hour survival compared to endotracheal intubation (ETI) for patients with out-of-hospital cardiac arrests (OHCA). 2. However, a similar English randomized controlled trial found no difference in favorable neurological outcomes 30 days...
1. In this multicenter, longitudinal, serial cross-sectional analysis, there were 457 hospitals across 43 states that reached a monetary settlement with the Department of Justice (DOJ) totalling more than $250 million. 2. Following the announcement of the investigation, there were significant reductions in the number of primary implantable cardioverter-defibrillators (ICDs)...