Tag: infertility

1. In couples obtaining infertility treatment, folic acid and zinc supplementation in men did not lead to a significant improvement in semen quality or the rate of live birth, when compared to a placebo 2. A mild increase in sperm DNA fragmentation was found in the supplementation group. Evidence Rating Level: 1...
1. In couples obtaining infertility treatment, folic acid and zinc supplementation in men did not lead to a significant improvement in semen quality or the rate of live birth, when compared to a placebo 2. A mild increase in sperm DNA fragmentation was found in the supplementation group. Evidence Rating Level:...
1. In a prospective cohort, a diagnosis of endometriosis was associated with a higher risk of subsequent infertility. 2. This association was only statistically significant for women under 35 years old. Evidence Rating Level: 1 (Excellent) Study Rundown: Endometriosis, a condition in which endometrial tissue exists outside of the uterus and affects...
1. Among infertile couples with poor prognosis and/or severe male factor infertility, intracytoplasmic sperm injection (ICSI) was associated with higher fertilization, implantation, and pregnancy rates. Original Date of Publication: April 1993 Study Rundown: Male factor infertility is a vexing problem in the field of reproductive endocrinology and infertility. Couples with severe...
1. Male mice lacking either the Ppp3cc or Ppp3r2 genes, which encode parts of the sperm-specific calcineurin protein, produced sperm with rigid midpieces and were infertile. 2. Wild-type mice treated with cyclosporine A (CsA) or FK506, nonspecific calcineurin inhibitors, produced similarly defective sperm and displayed infertility which was reversible...
1. Women with luteal phase deficiency were more likely to have higher Mediterranean diet scores and consume more fiber. 2. Vigorous exercise was negatively associated with luteal phase deficiency. Evidence Rating Level: 1 (Excellent) Study Rundown: Infertility is defined as the inability to conceive after 12 months of regular unprotected intercourse or...
1. Mutations in TEX11 were found in 2.4% of infertile men with non-obstructive azoospermia without another known cause. Evidence Rating Level: 3 (Average) Study Rundown: Azoospermia refers to the absence of sperm cells in the semen. This may be due to an obstruction, or an inability to produce mature...
1. Among infertile couples undergoing intrauterine insemination (IUI), those randomized to ovulation induction with low-dose gonadotropins achieved a higher live birth rate than women on clomiphene. 2. Low-dose gonadotropin stimulation was associated with similar incidence of multiple pregnancy and multiple live births compared to clomiphene. Evidence Rating Level: 1 (Excellent)  ...
1. Over a third of couples eligible for expectant management of unexplained fertility were treated; prognosis was often not calculated and/or expectant management was frequently not recommended. 2. Couples who were expectantly managed had comparable pregnancy rates to those who were overtreated. Evidence Rating Level: 2 (Good)   Study Rundown: The use...
1. A normal variant of a gene responsible for cell-cell adhesionwas associated with primary infertility in northern Chinese women with ovarian endometriosis.  Evidence Rating Level: 3 (Average)         Study Rundown: Endometriosis, a disease characterized by the presence of endometrial tissue outside the uterine cavity, is seen in 5-10% of...