Tag: neonatal

1. Systematic review with meta-analysis shows no statistically significant difference in morbidity and mortality outcomes when comparing use of low versus high FiO2 during initial resuscitation of preterm infants (<35 weeks gestational age). 2. Subgroup analyses of data on infants <32 weeks and ≤28 weeks also showed no difference in...
1. Patients born both extremely premature and with severe growth restriction were found to have decreased level of functioning in multiple cognitive domains when assessed at 10 years old. 2. In addition to cognitive delays, patients born extremely premature with severe growth restriction were found to have a myriad of...
1. In pregnant women, treating subclinical hypothyroidism or hypothyroxinemia with levothyroxine did not significantly impact cognitive outcomes in children up to age 5 years of age when compared to placebo. 2. No significant adverse maternal or fetal/neonatal events were described as a result of treatment. Evidence Rating Level: 1 (Excellent) Study Rundown: Adverse outcomes,...
1. Parents who used a midwife to deliver their child and those who delivered at home or in a birthing center were at a significantly increased risk of refusing to provide their newborn with vitamin K prophylaxis. 2. Children who did not receive vitamin K prophylaxis at birth had an increased...
Classics Series, Landmark Trials in Medicine
Image: PD 1. During the 1990-1998 study period, which included the 1996 initiation of national Group B Streptococcus guidelines, a significant, 65% decrease in early-onset neonatal disease was observed. 2. During the study’s final year, an estimated 3900 early-onset neonatal GBS cases along with 200 early- and late-onset neonatal deaths were...
Image: PD 1. Plastic bags made from polyethylene reduced hypothermia among premature and low birth weight newborns by 26%.  2. The use of plastic bags for hypothermia prevention was not associated with hyperthermia or skin side effects. Evidence Rating Level: 1 (Excellent)  Study Rundown: Neonatal hypothermia has been associated with serious adverse outcomes,...