Tag: prostatectomy

1. 3-year event-free survival rates were significantly greater in the 18F-fluciclovine-PET group compared to conventional imaging. 2. Adverse reactions and toxicity levels were similar between the two groups. Evidence Rating Level: 1 (Excellent) Study Rundown: In patients with prostate cancer, prostatectomies are often followed with adjuvant or salvage radiotherapy. Postprostatectomy radiotherapy has...
1. There is no evidence that adjuvant radiotherapy improves survival compared with early salvage radiotherapy following radical prostatectomy with localized or locally advanced prostate cancer. 2. Pre-surgical PSA, Gleason score, seminal vesicle involvement and surgical margins did not influence the effect of adjuvant radiotherapy on event-free survival. Evidence Rating Level: 1...
1. Among men under 75 years of age with localized prostate cancer, radical prostatectomy was associated with a significant survival benefit compared to watchful waiting. 2. In patients who underwent radical prostatectomy, extracapsular extension and a Gleason score of 8 or 9 were strong indicators of poor prognosis. Evidence Rating Level:...
1. Among prostate cancer patients treated with robot-assisted radical prostatectomy, the use of preoperative prostate magnetic resonance (MR) imaging significantly reduced the risk of postoperative positive surgical margins. 2. Preoperative MR imaging showed a high negative predictive value for the presence of positive surgical margins. Evidence Rating Level: 2 (Good) Study Rundown:...
1. In a retrospective cohort of 1107 patients with lymph node invasion following primary prostate cancer treatment, the use of adjuvant radiotherapy was associated with a significant improvement in cancer-specific mortality. 2. Two sub-group of patients: 1) Patients with positive lymph node counts of <2, Gleason score 7-10, pT3b/pT4 stage...
Image: PD 1. Men with localized, non-metastatic prostate cancer who underwent radical prostatectomy demonstrated lower mortality rates compared to treatment with radiotherapy. 2. No treatment advantage between radical prostatectomy versus radiotherapy was observed in metastatic prostate cancer patients. Evidence Rating Level: 2 (Good) Study Rundown: Current mainstay treatment for prostate cancer is surgery...
Image: PD 1. Prostatectomy did not significantly reduce all-cause mortality or prostate-cancer mortality when compared to observation 2. These findings support conservative management for men with localized prostate cancer, especially for those with PSA values less than 10 ng/mL and low-risk disease Original Date of Publication: July 19, 2012 Study Rundown: The incidence of...
Jan 31st – NEJM - While 15-year outcomes are similar, at years 2 and 5 years radiotherapy is superior to prostatectomy in urinary and erectile functions. Image: CC/Nephron. Gleason 4 prostatic acinar adenocarcinoma. 1. At 2 years and 5 years from diagnosis, radiotherapy is superior to prostatectomy in such functional outcomes as urinary...